Can i run the same game twice on my pc ? Nope.
Wait, what? You must really not know a thing about hardware.
Most aftermarket/off the shelf graphics card these days support 2 monitors - that's 2 separate displays. Laptops have HDMI out for instance that lets you extend your display to a TV or another monitor as well. If you're counting, that's 2 displays at once on a laptop.. hell laptops have been able to do this for years and years, and at resolutions higher than the GamePad's. And don't forget the DS had two screens with different pictures being shown on both, plus touch on one. Nintendo has the whole multiple screen thing down by now, without a doubt in my mind.
"It's crazy because the game is running in full HD [on the television], we are streaming another picture on the GamePad screen, and it's still 60 frames per second. And the latency on the controller is just 1/60 of a second, so it's one frame late. It's crazy, it's so fast. It's almost instant. That's why it responds so well. So it can be used as a real game-design thing."
http://www.nintendol...160_of_a_second
And as someone else mentioned above me, there IS support for 2 GamePads at once, just no launch games make use of it as far as I'm aware.
As for running the same game twice on a pc.. I multibox WoW with my account and my brothers account on my computer with no issues. Multiboxing is where you play multiple different accounts at once (read: the game itself is running multiple times), either on one computer or multiple computers.
Edited by bornsupercharged, 29 October 2012 - 08:26 AM.