New to the forums so forgive me if these have been mentioned already.
New Zelda game (Hyrule Warriors looks nice, but its another game with a Zelda skin)
If a Zelda remake: OoT with a nice graphics makeover, I think WW already looked good.
Metroid a: if a Prime type stick with GC controls or b: Other M type, but with open world with items found not told when you can use them with no Motion Contol/FPS hybrid.
Kid Icarus perhaps as some type of Open World with Ancient Greece setting
Since Nintendo appears tight with Sega: Skies of Arcadia
Maybe Rygar? I know it Tecmo but have a soft spot since it was my first NES game I bought.